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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd766733bc3b605e5817376a7300e3cf7893ed82b6b5b272da3b7e83c6183cdce' 
  AND token = '8AWrmYrGnhc/PDC/7HJ6W3Lw9P6lqvd8uOUU/vV3z3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}