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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2210ea423c5a7e9a53d0667e7a3e2486437da4d9d8750224ca2e4b929fb0a7a2' 
  AND token = 'ODv4B96aihJ9B4/QiNMD3X/IrgQkRkOkZnG3oAG6z38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}