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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a33c526a3c9272383f4405d3315fb0eec62fab33283e881e80ba9feeea1306' 
  AND token = 'qS+XGcaVCWsXg/AnXB1IOIJ7oC3kHe/anCOS8/CqJEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}