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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f2a71a396fc0eaa9e57edf495ec82de88df2e7b145679261f93ddb52de04a8b' 
  AND token = 'cuhCeLueIoeftTq6vPvZ/UlyuQqcuCj6LkgWlQH45Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}