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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f21c9098c0146eb41e5e9ef045ab5f15a39fa2741b91cddf39aa430e981236b' 
  AND token = 'lfLL6tjSgOP27k7SYvc8dqLxO/UV/3vhyoz/2m3hrNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}