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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cda2bc15caf1f63536f8e7816961e0de71b5dac5a775045a040a7bd5b4a01e' 
  AND token = 'kfBY92DPvO3l1UhXd6R81ujUVUuLPHSeu5+grXNqCoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}