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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f260976a0eb32dffd949812159384d66f20ba9756e127b115495e350e44d84' 
  AND token = 'uEeI/wm50W3AJ4PrGYq8kVwKy3NpO4oM8eMewutyq1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}