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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e866e2c08d9beff30c9be658458bf88e356ef59432e1766790975dd646175a9' 
  AND token = 'xIIYI8ni42ZqO+YZaDFrEXFjuNg2Y0P2NS0jkGxRfUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}