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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3e9185adbe44e3ec233518dc64e53318f636fa7ea54d96f4ffe004d442160d' 
  AND token = '+K9vnt9uzYf5BqgA1a18bAzv7Nbuey9t41AghiXrwcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}