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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e94a8fa1f768bc3fe7679ac4fd5023f493b4f5188c53bb2183b17269fe74322' 
  AND token = 'C7DpwGZ+OeDDKHhiwZzZ4TmUr3e0Tz+IFTxXs9oLEbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}