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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b620686f67015a5549b31d63b047c14a99f0989c14699044ebe5b003e5a471' 
  AND token = 'JZc1nEXTF1W+7i2ZYtR42Hwbxes6gH63L1ewNaxVD7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}