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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04182d1b39aabecfc786265769b16b2c0e675321d3a3921307a27228581d5dea' 
  AND token = 'dLA89ERbcsKmFLEZH5NhHKNa24h2kvSyzRJDBNaiCIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}