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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c922da15307514547c8408cd72e56aaff975e5eb721d77617108420ad64cfc3c' 
  AND token = 'XQQsCl/+dqpEJJOHInisJJsNWyJ2khEo7pESY6RD2EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}