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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2260cf2703056f2fdc497aa705e0e655a6dc76d46648e127a00b4740ace803f4' 
  AND token = 'TAE3lzlkuFPoZrynRYBSEBlnujN3SGUIM5D3kEPhcrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}