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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a05e1bb0f36944c2e40808474b38ff521793d3882397289de687ea751f15a2' 
  AND token = 'Ppnl2Wt9ntr4EAXtM0OpNJrwvkoKiqHdxx7CQNBAz2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}