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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb1f36fd0f10bcab03c0a278b9987d277dbe1f5f545857b32f92f88cf4cf437' 
  AND token = 'dTZcYMAf4Tcx+l8tqX/9TZy1eF6XYzKSRPxNf9G1aYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}