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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51a4b9f280599b9e6b13c050b82f2db72da5bd6eeb1024adc3f001d9042f771' 
  AND token = 'jrI35V4HI7P7UA071wi8lEy67IBXLeS7kfQfrKZvGWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}