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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2235ddbd689447c99bf4fe491fae9a9b89812fcfdc0f99b000f25ac947260a8f' 
  AND token = 'LUcEIg7Bc1w1e1mi/wtF5Dmp2Dz68oxcM8qcE0aPASw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}