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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557a04541f65eca6b9b09ed03794c8cb8f82a4429eba77f0423e396b8b35337f' 
  AND token = 'WfY3lu2H53nBTf2TC3e8IEY1yYWH3K2jglIB4ZOBFlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}