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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bf854193b1db8198740443ec413b05d7a0f85e2a79ea1d6abcd86ce8aeccf51' 
  AND token = 'oXB3RHIT/rY/ZJVfEcTL8yY1bcicvop3Rxd3OP6DSiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}