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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27682d8e76fc7272d9dec3d2cfa94bf8130b6f015fe80570e16531f093bfd0e' 
  AND token = '344/TKzd4UW/9+jjlhLE4x8iaUmPGaLm7x/rvx6AASY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}