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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41fa2a5a12b522e5669d254c592c21f4c24cd551fe9b4ddeac45c73e6e71fc6c' 
  AND token = 'vJE5S2Z+zVmXbgDCQcdF1OWYM3/OK/eB2safm0ebGCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}