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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c091e620a223d62e4f9acf8d7b2ebb2b1336792df0b28d204c5148ee34a59e' 
  AND token = 'KQkTzJDyJH4EPwUjBTM0+rxOSAbYMWVtEFiaLGtEiqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}