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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52f7bcaf1b0b2bd478f4b2b264e58570b95818a99c2dd3c64009a29beb366be' 
  AND token = 'vFgO6W/IEQnvrmEJ8ZVAa0JSF0j+OvugCCRtmn29wRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}