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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f813e6b67eea9d6ebb48d811ad3c2ec7cb0af7f84e58beda4da82404cb8d25' 
  AND token = 'iwMlWjRqv/2TpfdfEsQ6N7xYO5ZSh1u4oqyxEal24yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}