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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b9edea8115386113d7c6ba4c77f2ae89ee891449c431fbdcc5fdf7c2c6a918c' 
  AND token = '9wF1roGuDoliKVgO9fV+T97ReiwsNbfXTPP1cfXxOpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}