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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1294036b3ee04ee3b10df81d93df47dd7941c620e7196beea1161e376b85deb5' 
  AND token = 'H0JBfIHv+acxYemdGNBR2XYhNbAj0ln+D9sfGfQiYpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}