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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a42470265419944375faf1310c5f7bb36336afa89cbf354af461c3bec1408ac' 
  AND token = 'Gp/rENTGKo0AEP88tb4Gxr0W7dp6xPaZqIhIt+yzVdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}