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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de6cf0c6d48e5182349014c267d7943c69280b1d07f4842c9fe5d28d0b75161' 
  AND token = 'nNRZqiaFxc/t5LcLlFgFdZqse+rdtmDsnDadmlu/RZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}