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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465da11f841602d96b37d3462dfbe869d51a0ad049d06c2ba2212e416174f892' 
  AND token = 'Hby71hhS8UJhT6DtlOEqwYeRj8fba5DD09SslVx3XQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}