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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e41828e1d980b6ea6160d51b437de859c8a4dd3a5020b6d47346d4b8b0c69a0e' 
  AND token = 'ZTZ1lx3wfmBRtVol8Ie3NSqK83SVkG0ThZ1vWXJzGW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}