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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12c54d2e645630cab50047ee9f78a3e00f03351f399f5d529ac641497355fb9' 
  AND token = 'GnR0xJMbsPA+oa5VxPAJLJSSfhi3mANCbFG+BOoaPM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}