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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bcc1e1dd03adef111b754bf6162a3b1e6dd72d8c0209472e9286736f77d3d13' 
  AND token = 'W9zP1Nbv39RHG6US0QKQEQ5yh59yxSahWTIIZ1med4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}