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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d41cf230873ece56c46da44813c3737ad73c2dedcacbf2a893706ac718e2c35' 
  AND token = 'cg1oM66Q3VeZ/2Yy3OQKHwCZhNXmL+SphuaqK9+872E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}