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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e8c4ce4b578c77e4030d59246bb96cf69fc03ffd70689f8b51322e037ddaa6' 
  AND token = 'zGPn8vrIYKc9lRczU3URA/I89WbV+4OG1RwEpqIqWkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}