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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e14dfe653f521b2e9bdbf4a3042559ce592022164a0ad4e61bcbb60221828c3' 
  AND token = 'oCQP9XVa00pi8YVuFR+mtU3/VF6GVulqKDhzA3rdmO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}