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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5c99583777e08a6da34daae791b783a49c4f3ff67da1686d78f0e337f26884' 
  AND token = 'T3Tnjyhok5T0Ub1E0PRWFUlGh7BvS04lZc5WbBOBEzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}