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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73776f20b91be6b285f3a13cc96c4deab7b5ebdb9e5415d31882d11647247a04' 
  AND token = 'UQdcCUrwn25Gk9rNSaNXZtEqRYMNNN36t7Lj5c3FIgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}