SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05213ae459c629903b881138a2142a8bd4e98bb2ef2edccff429ebea1020115a' 
  AND token = 'IfD9M2ASRVPDlTR+Gq8M7YndPRnRXAW/Cah0+R0dFng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}