SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b4f51401b30946feb2ea004621127ec019f80bb98e664031e088362a28539b' 
  AND token = 'jXnk3y9AKVw1otX3auXnUWqDvpd6xRUKgKOdE5r2PQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}