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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04fc1538b8d7b981cd436807aac993346d814e12430c0987be3fbcd4e9131552' 
  AND token = 'S4/IkPoG5E+tcYHevpj+a6q0oI/smITUa/jhq292Vng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}