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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ff6b8c99e1cf557fa938401f38c4c750f2c170983f332381cdecfb3142de2c' 
  AND token = '9PkEb+5bqgkuSRSvvv0BlBFZnepxV0aN9/u3DdpZdzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}