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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e18c0d7909a393db244609f667f8edeca7ff9db497c34d5b15c329b63d8e0e' 
  AND token = 'FxMm7OOJ8SAFHos9pr3zTYIWlQZ5lKbgmteVT4AsMxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}