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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5649d34a56c634ed1076ef9d723c9f4e12e1c1aab14eeb195b5d5566865023' 
  AND token = 'CGtcWalXdSV2htmoceDhGHRmDx/j52sos7jVjGDRvEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}