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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ed785c093fc41b8aaba7a6a297998cec28da97220a398c9cea7e6ede8b454e' 
  AND token = 'mrepbC69N7H6DHCSzksjqDNUIPKAmBmnThCZnKijna8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}