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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b73c3d5c0634b8e569afcd69d12e5595dffc2d1b046bd0d6f48090de612b0d' 
  AND token = 'NTCBOuv72jQ1x6GS92KzbYPUqzbuwXY7cMcmJklbIK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}