SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b67c44acd04e1f95a909e02c71390599489b2b45981b601b31f877461a07c6' 
  AND token = '0hRNyf6ppM1t47XdOQTCX2X4DOd+BLJqFuhKp6uT4Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}