SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e592051d642948aa4c2c8234a613aba64d587fac1584d57a48593a4a5fdf9c65' 
  AND token = 'ORU2rWzQiL8Hvh1BOGwBldSVtifcGDlfCh0QxBI0+A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}