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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431aa2f0e649fc6a3da24d205bd6065ef427c100d9b5f7a92deb6a88f7e9f2e6' 
  AND token = '4BfeeB9LzSSG8wHttkUkZ8RFKT/FekFVdFmzxf+wcjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}