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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ebaf116fa58acb985c5e06641d87e4fb8fb383e186a6e9290dfebf5301a229e' 
  AND token = 'w5+M07JR3XBW/5WhZ1pd7e2hbiv5stMKXC0/RAFnBI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}